4.9/5
Trusted by 100,000+ women
HRT and libido –
The connection your doctor probably didn't mention.HRT and libido.
The connection your doctor
probably didn't mention.
When estrogen and progesterone decline, desire doesn't just drop — it disappears entirely. HRT doesn't force it back. It rebuilds the biological conditions that made it natural.
bring the spark back with Oestra®
HSA/FSA eligible
Made in U.S.A
Compounded in a Licensed U.S. Pharmacy
503A U.S. pharmacy. NABP, LegitScript & PCAB certified.
Clinician-Approved Prescription
Clinician-Approved Prescription Treatment
HSA/FSA eligible. Secure.
Bioidentical Estradiol + Micronized Progesterone
Bioidentical Estradiol + Micronized Progesterone
Clinically proven & third-party tested.
How It Works
Libido is a health marker.
Not a relationship problem.
It starts in the brain, not the body.
Estrogen fuels the “I want” chemistry. When it declines, desire often does too. You can still love your partner and feel nothing. That’s your hormones.
Then the nervous system follows.
Progesterone helps your body relax enough to receive desire. When it's low, your body stays in stress mode.
Then the tissue responds.
Estrogen supports blood flow, sensitivity, and lubrication. As it declines, so can responsiveness.
Most women aren't told this. They're told to relax more, have more date nights, try a glass of wine. As if the problem is effort. It isn't.
When hormones decline, desire declines. It's physiology.
See If Oestra® Is Right for You
Restore the hormones. The rest follows.
— Dr. Sarah Daccarett
How Oestra® supports your hormones
Progesterone
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Progesterone
Estradiol
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Estradiol
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Ellagē® Base
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Ellagē® Base
Ellagē® Base
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Ellagē® Base
Bioidentical
Progesterone
Hormone Support
Bioidentical progesterone for protection and balance
Bioidentical
uterine support
calming support
Ingredient Sourcing
Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
Third-party labs verify that the strength in the bottle matches the prescription on the label.
Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Bioidentical
Estradiol
Hormone Support
Bioidentical estradiol — the body’s most active estrogen
Bioidentical
systemic effect
plant-derived
Ingredient Sourcing
Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
Third-party labs verify that the strength in the bottle matches the prescription on the label.
Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Supports brain, bones, metabolism,
mood, vaginal tissue, and long-term
vitality.
Ellage® Anhydrous
Base
Delivery System
Ellage® anhydrous base for enhanced absorption
anhydrous
pH-balanced
stable delivery
Why it matters
100% paraben-free, fragrance-free and contains no endocrine disruptors.
Water-free and designed for sensitive vaginal tissue.
Enhances absorption, prevents leakage, and maintains natural pH for consistent systemic hormone levels.
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Supports Natural Testosterone
Hormone Pathway
Progesterone supports natural testosterone production
No Synthetic Testosterone
self-regulated
downstream conversion
Why no added testosterone?
Progesterone is a precursor to testosterone.
Restoring it allows your body to regulate its own optimal levels — supporting libido, strength, and energy naturally.
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Bioidentical
Progesterone
Hormone Support
Bioidentical progesterone for protection and balance
Bioidentical
uterine support
calming support
Ingredient Sourcing
Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
Third-party labs verify that the strength in the bottle matches the prescription on the label.
Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Bioidentical
Estradiol
Hormone Support
Bioidentical estradiol — the body’s most active estrogen
Bioidentical
systemic effect
plant-derived
Ingredient Sourcing
Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
Third-party labs verify that the strength in the bottle matches the prescription on the label.
Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Supports brain, bones, metabolism,
mood, vaginal tissue, and long-term
vitality.
Ellage® Anhydrous
Base
Delivery System
Ellage® anhydrous base for enhanced absorption
anhydrous
pH-balanced
stable delivery
Why it matters
100% paraben-free, fragrance-free and contains no endocrine disruptors.
Water-free and designed for sensitive vaginal tissue.
Enhances absorption, prevents leakage, and maintains natural pH for consistent systemic hormone levels.
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Supports Natural Testosterone
Hormone Pathway
Progesterone supports natural testosterone production
No Synthetic Testosterone
self-regulated
downstream conversion
Why no added testosterone?
Progesterone is a precursor to testosterone.
Restoring it allows your body to regulate its own optimal levels — supporting libido, strength, and energy naturally.
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
Designed for the symptoms that actually disrupt your life
Oestra® supports:
Healthier libido and sexual comfort
Clearer thinking and stable moods
Deeper, more restorative sleep
Steadier energy and metabolism
Bone and brain protection
Vaginal health — without separate creams
This isn’t about chasing one symptom.
It’s about restoring steady hormone levels so your body can function normally again.
Find Out If You’re a Candidate
Measured improvements after 6 monthsHormones don't just affect desire. They affect everything.
In a 6-month outcomes review of women
using Oestra®:In a 8-week outcome review of women using Oestra®:
7575%
improved sex drive & arousal
9797%
resolved vaginal dryness
8080%
improved sleep
7979%
improved mental health
7070%
better skin & hair appearance
*Results based on Inner Balance patient-reported outcomes. Individual results may vary.
Hear from 5000+ women
4.9/5
5,695 Reviews
“I've lost weight, my energy is back, and my depression is gone...”
MARCIA
VERIFIED PATIENT
“The symptoms were just insane. I couldn't explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It's like I'm waking up from a foggy dream.”
KIRALEE
VERIFIED PATIENT
“In the first couple days that I took it, I had 110% energy back. My husband was like 'Whoa I haven't seen this in you in a really long time.' It just keeps getting better and better.”
HAYLEY
VERIFIED PATIENT
“I can honestly say that after 3 days, I said to my husband... I don't know how to explain it, but I feel myself again.”
STACEY
VERIFIED PATIENT
“I already feel a lot of my pain decreasing, I'm sleeping better, and I'm able to mentally focus.”
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VERIFIED PATIENT
“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”
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VERIFIED PATIENT
“I absolutely adore Inner Balance. I started it and I feel amazing. It's been 6 months now. If you're thinking about it, stop thinking and just do it. You won't regret it.”
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VERIFIED PATIENT
Do you need added testosterone?
Do you need added testosterone?
Many women are told testosterone is the missing piece. But in many cases, low testosterone is a downstream effect of low progesterone and hormonal imbalance.
Oestra® does not contain added testosterone. Instead, it restores progesterone — which serves as a precursor hormone in your body’s natural testosterone pathway.
When hormone balance is restored, many women notice improvements in:
Libido
Motivation
Energy
Muscle tone
Without the risks often associated with testosterone creams, pellets, or injections.
For women who truly require additional testosterone, our clinicians can evaluate that separately. Balance first. Add only if necessary.
“I’m exhausted no matter how much I sleep.”
“My periods are heavier and unpredictable!”
“My brain fog just won’t lift.”
Vaginal doesn’t
mean “local only”.
Oestra® is designed for systemic absorption — delivering hormones directly into the bloodstream while bypassing the liver.
That means:
Steadier levels
Less estrone conversion
Fewer side effects
Smarter delivery is the difference.
check my eligibility
Dr. Sarah Daccarett, MD
Backed by science.
Formulated by women’s health experts.
Inner Balance was founded by Dr. Sarah Daccarett, MD, a board-certified specialist in women’s hormonal health and longevity medicine.
Her research has been published in leading medical journals, and she is licensed to practice medicine in 48 states.
“I founded Inner Balance because women deserve better
– better information, better care, and better outcomes.”
featured in
Real guidance from the
doctor behind Oestra®
Dr. Sarah created Inner Balance to deliver a different kind of hormonal care.
Her approach centers on bioidentical hormone enrichment, safe delivery methods, and treatment guided by how women actually feel - not just lab numbers.
After treating thousands of women, a clear pattern emerged — anxiety, poor sleep, brain fog, and low energy, often dismissed despite "normal" labs. Existing hormone therapy felt fragmented and overly complex. Oestra was created to simplify care and actually address how women feel.
Lab results don't always reflect how hormones fluctuate in real life. Many women feel unwell despite being told everything is "normal." Symptoms like brain fog, anxiety, and poor sleep are often more accurate indicators — and should guide treatment decisions.
Traditional hormone therapy often targets a few symptoms like hot flashes or sleep. Oestra takes a broader approach, supporting brain function, metabolism, energy, skin, and overall wellbeing. It's designed to help women feel fully balanced — not just manage isolated symptoms.
Hormone therapy is often fragmented into multiple prescriptions, lab tests, and trial-and-error adjustments that can take years. Oestra® was designed to simplify the process into a single, streamlined approach that fits into your life without unnecessary complexity or cost.
Oestra® combines estradiol and progesterone into one daily treatment, replacing multiple prescriptions. This makes therapy easier to follow and more effective long term.
Estradiol and progesterone work together to support the entire body — including brain health, metabolism, skin, sleep, and the nervous system. Using both helps restore balance more effectively than treating hormones in isolation.
Vaginal delivery allows hormones to be absorbed directly into the bloodstream, supporting more stable levels and consistent symptom relief. Oral and topical methods are less efficient.
Many women notice early improvements in sleep and mood within weeks, with deeper changes like skin and cognitive function improving over 2–3 months.
Your care begins with a clinician reviewing your assessment. Your prescription is compounded and shipped directly to you, with ongoing adjustments and access to clinical support as your needs evolve.
Oestra® uses bioidentical estradiol and micronized progesterone, identical to the body's natural hormones. Treatment is monitored and adjusted over time, focusing on safe, long-term support.
Oestra® restores progesterone, which the body can naturally convert into testosterone as needed. This supports balance without forcing levels and helps avoid side effects like acne, hair loss, or weight gain.
Oestra® is a prescription-based hormone therapy reviewed by a clinician and tailored to your symptoms. It's compounded in a licensed pharmacy using pharmaceutical-grade ingredients.
Simple, transparent pricing
$199 per month for your first 6 months
$199/month for your first 6 months
Then $99.50 per month
Prescription treatment
Free & fast shipping
Unlimited clinical follow-up
HSA/FSA Eligible
No insurance needed
Dose adjustments if needed*
Cancel
anytime20% off any supplement in FullScript
*Dose adjustments may incur an additional cost.
Getting started is simple
Step 1
Complete our 2-minute health quiz
Help us understand your symptoms to see if Oestra® suits you.
Step 2
Receive your
prescription treatment
A licensed clinician evaluates and determines next steps. Once approved, prescription is delivered.
Step 3
Start treatment and
get ongoing support
Our clinical care team is always here for you whenever you want to check in.
Smarter hormone therapy. Finally simplified.
Hormone balance. Simplified.
One cream. Two bioidentical hormones.
Steady systemic support — without the patchwork.
See if Oestra® is a better fit for you.
Start the 2-minute quiz
No insurance needed. Cancel anytime.
Questions?
TREATMENTS & SAFETY
Yes. Oestra® contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.
Yes. Hormone therapy is one of the most extensively studied treatments in medicine, with decades of research supporting its safety when used under medical supervision. Oestra® uses bioidentical estradiol and micronized progesterone — hormones identical to those naturally produced by your body — to support healthy hormone balance. If you ever choose to stop treatment, you can do so at any time. Your hormone levels will simply return to their natural baseline. Our medical team monitors your treatment and guides adjustments to ensure it remains safe and effective for you.
It goes beyond that. Oestra® is made by a 503B FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.
Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of personalized medicine with pharmaceutical-grade oversight.
Oestra® uses only bioidentical hormones—compounds identical to the ones your body used to make, derived from plant sources. In plain terms: they’re natural to your body, better tolerated than synthetics, and designed to restore—not override—your natural balance.
Two major ways:
– Delivery: Oestra® is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.
– Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.
Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra® gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.
No. Lab work is not required to begin treatment. Your care is guided first and foremost by your symptoms, medical history, and a comprehensive clinical review — not just lab numbers. Many hormone imbalances can be identified clinically, and you can begin treatment without testing. If you’d like deeper insight, we do offer convenient lab testing, and a full clinical review of your results is included in your care. Labs are optional — your journey with us will be personalized either way. You can start feeling better now, and add testing later if and when it makes sense for you.
No. In fact, Oestra® is designed to help correct estrogen dominance — not cause it. Estrogen dominance often occurs when progesterone levels are too low relative to estrogen. Oestra® provides both progesterone and estradiol in a carefully balanced ratio to help restore hormonal balance and calm the fluctuations that can drive symptoms. Because the hormones in Oestra® are delivered vaginally, they are absorbed efficiently and avoid the liver metabolism that can sometimes contribute to hormonal imbalances. This allows for more stable hormone levels and a more balanced response. Our medical team also personalizes dosing and monitors your progress to ensure your treatment remains balanced and effective for your body.
Most women tolerate Oestra® very well. As your body adjusts to hormone optimization, some women may experience mild breast tenderness or light cramping during the first few weeks. These symptoms are typically temporary and resolve quickly. Less common side effects may occur but are usually mild and easily addressed with simple adjustments to dosing or supportive recommendations. Our medical care team monitors your progress and is here to guide you every step of the way, ensuring your treatment remains comfortable, effective, and personalized to your needs.
No — Oestra® is non-contraceptive and does not suppress ovulation.
Yes. Bioidentical hormones are safe to take for decades and actually support longevity and disease prevention.
GETTING PRESCRIBED
Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a licensed clinician reviews your info, your prescription is sent to the pharmacy and shipped directly to you. You’ll receive a 3-month supply as part of a monthly subscription.
Yes. Every Oestra®prescription is reviewed and approved by a licensed clinician. You don’t need to book a separate appointment - your quiz responses help us determine if it’s safe to begin treatment and ensure you're a good candidate for our starting dose.
We don’t isolate hormones - we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra® is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.
PRODUCT USE
Apply one pearl-sized pump of cream daily to vaginal tissue using your finger. An applicator will be available in the future, but for now, we recommend manual application for best results.
You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra® isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.
Oestra® is delivered every 3 months, and billed monthly. Your membership includes treatment, pharmacy processing, shipping, and unlimited clinical support.
ELIGIBILITY & ACCESS
Not at all. We work with women as young as 18. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.
It’s not—because insurance typically only covers the most limited options. Oestra® replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. HSA/FSA is also accepted at checkout.
Yes, we accept HSA/FSA directly at checkout. Most carriers accept prescriptions as eligible and we also provide a letter of medical necessity.
SHIPPING & DELIVERY
Yes. Shipping is always free—every Oestra® prescription ships at no extra cost.
Most orders ship within 3 business days after your prescription is approved. We like to give your pharmacy time to prepare everything safely.
Yes. Your order arrives in discreet packaging. The outside of the box is labeled Inner Balance, but it does not identify the medication or indicate what’s inside.