Treatments & Safety

Two major ways:
Delivery: Oestra™ is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.

Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.

Oestra™ uses bioidentical hormones, which are derived from plant sources and designed to closely match the hormones your body naturally produces. While technically created in a lab, bioidentical hormones are widely considered a more natural and body-friendly option than synthetic alternatives.

Oestra™ was designed to be a safer, more effective, and easier-to-use hormone therapy—without the compromises.

Here’s what sets it apart:

  • Plant-based, bioidentical hormones that mimic the ones your body naturally makes
  • Targets your most bothersome symptoms, like hot flashes, brain fog, mood swings, and low libido
  • Doctor-supervised care from providers trained in women’s hormones
  • Easy-to-use, daily vaginal cream —no pills, patches, or injections
  • No lab work required to start, and no in-person visits
  • Shipped in 3-month supplies for convenience and consistency
  • Transparent pricing with no surprise fees

Our goal is to offer a treatment that’s not just effective, but also supportive and sustainable—so you can feel like yourself again.

Yes. Oestra™ contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.

It goes beyond that. Oestra™ is made by a 503B FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.

Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of personalized medicine with pharmaceutical-grade oversight.

Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra™ gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.

Hormones fluctuate constantly—sometimes by the hour. That’s why a single lab test rarely reflects your true needs. Instead of chasing numbers, we start with your symptoms—what you’re feeling in real life—and fine-tune from there. It’s faster, more personal, and far more effective. You’re not a lab value. You’re a whole person, and that’s how we treat you.

Getting Prescribed

Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a board-certified provider reviews your info, your custom prescription is sent to the pharmacy and shipped directly to you.

Every Oestra™ prescription is reviewed and approved by a licensed clinician. You don’t need a separate appointment—your quiz helps us determine if you’re a good fit to begin safely.

We don’t isolate hormones—we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra™ is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.

If you’re experiencing fatigue, brain fog, anxiety, irregular cycles, or changes in skin, sleep, mood, or weight—it’s time. You don’t need to wait until your period stops or hot flashes hit. Hormone decline starts years earlier, and the sooner you start, the more protected and vibrant you’ll feel.

Product Use

Apply one pearl-sized pump of cream daily to vaginal tissue—using your finger. It doesn’t need to be inserted deeply. Absorption through this tissue supports whole-body hormone balance.

You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra™ isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.

Eligibility & Access

Not at all. We work with women as young as 21. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.

It’s not—but that’s often a good thing. Insurance typically only covers the most limited options. Oestra™ replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. We also offer referral discounts and 6-month satisfaction guarantees.

Yes. If after six months of consistent use you’re not satisfied, we’ll honor a full refund. We may ask a few supportive questions first to make sure there’s nothing we can adjust to help you feel better.

While we can’t accept HSA/FSA directly at checkout yet, many customers successfully submit their receipts for reimbursement. And our referral program helps you save too—both you and a friend get $99 off.

Shipping & Delivery

Yes! Shipping is always free. Your shipment includes a 3-month supply.

Once your prescription is approved, your prescription treatment is compounded and shipped within 3–5 business days. You’ll receive tracking details by SMS once your order is on its way.

Most U.S. orders arrive within 3–5 business days after shipment. We’ll send tracking info so you can follow along.

You’ll receive a 3-month supply of Oestra™ with each shipment. We bill monthly, and your subscription includes unlimited clinician messaging, check-ins, and refill coordination.

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