Bioidentical HRT, managed by a physician.
Estradiol + progesterone in one daily cream.
- HSA/FSA EligibleHSA/FSA Eligible
- 6-mo money back guarantee6-month money back guarantee
- Free, unlimited doctor visits & messagingUnlimited doctor visits & messaging



Our care team will work with you until you feel better.
Bioidentical Estradiol + Micronized Progesterone. Clinically proven & third-party tested.
Prescribed in 50 states. Compounded in a licensed U.S. pharmacy. NABP, LegitScript & PCAB certified.

90% of patients said the Oestra® treatment changed their life.
featured in











Here’s what happens after you order

Today
Check out today
No insurance forms, no phone calls, no waiting rooms.

Within 24 hrs
A licensed doctor prescribes your treatment
If anything needs clarifying, they’ll message you

In 3-7 days
Your Oestra treatment arrives
Shipped from a US-licensed, PCAB-accredited compounding pharmacy.

Months 1-6
Meet with your clinician
You talk through how you’re feeling and your dose gets adjusted if it needs to be. Then again whenever you want. Always included.
- HSA/FSA Eligible
- 6-month money back guarantee
- Free, unlimited doctor visits & messaging
Real guidance from the doctor behind Oestra®
Directly from the words of Dr. Sarah Daccarett.
After treating thousands of women, a clear pattern emerged — anxiety, poor sleep, brain fog, and low energy, often dismissed despite "normal" labs. Existing hormone therapy felt fragmented and overly complex. Oestra was created to simplify care and actually address how women feel.
Lab results don't always reflect how hormones fluctuate in real life. Many women feel unwell despite being told everything is "normal." Symptoms like brain fog, anxiety, and poor sleep are often more accurate indicators — and should guide treatment decisions.
Traditional hormone therapy often targets a few symptoms like hot flashes or sleep. Oestra takes a broader approach, supporting brain function, metabolism, energy, skin, and overall wellbeing. It's designed to help women feel fully balanced — not just manage isolated symptoms.
Hormone therapy is often fragmented into multiple prescriptions, lab tests, and trial-and-error adjustments that can take years. Oestra® was designed to simplify the process into a single, streamlined approach that fits into your life without unnecessary complexity or cost.
Oestra® combines estradiol and progesterone into one daily treatment, replacing multiple prescriptions. This makes therapy easier to follow and more effective long term.
Estradiol and progesterone work together to support the entire body — including brain health, metabolism, skin, sleep, and the nervous system. Using both helps restore balance more effectively than treating hormones in isolation.
Vaginal delivery allows hormones to be absorbed directly into the bloodstream, supporting more stable levels and consistent symptom relief. Oral and topical methods are less efficient.
Many women notice early improvements in sleep and mood within weeks, with deeper changes like skin and cognitive function improving over 2–3 months.
Your care begins with a clinician reviewing your assessment. Your prescription is compounded and shipped directly to you, with ongoing adjustments and access to clinical support as your needs evolve.
Oestra® uses bioidentical estradiol and micronized progesterone, identical to the body's natural hormones. Treatment is monitored and adjusted over time, focusing on safe, long-term support.
Oestra® restores progesterone, which the body can naturally convert into testosterone as needed. This supports balance without forcing levels and helps avoid side effects like acne, hair loss, or weight gain.
Oestra® is a prescription-based hormone therapy reviewed by a clinician and tailored to your symptoms. It's compounded in a licensed pharmacy using pharmaceutical-grade ingredients.
- HSA/FSA Eligible
- 6-month money back guarantee
- Free, unlimited doctor visits & messaging
FAQs
Getting Started
Safety & Ingredients
