Endometriosis pain isn’t normal, and birth control isn’t your only only option.

If nothing has worked, you’re not alone — and you’re not out of options. You shouldn’t have to live in pain, exhausted, bloated, and planning your life around your cycle.

Made in U.S.A

Clinician-Approved Prescription

Bioidentical Estradiol + Micronized Progesterone

Estrogen is one of the most effective longevity interventions for women.

FDA announcement, November 2025

Endometriosis is more than pain—it’s inflammation driven by hormones

Endometriosis isn’t just a reproductive issue. It’s chronic
inflammation—and hormones play a major role.

When progesterone is low or not working properly, the body can’t regulate the endometrial tissue the way it should.

Most treatments don’t fix this.
They suppress it.
Oestra is different.

Oestra cream jar

Once a day application.
Hormone balance, simplified.

Our Solution

A different approach to endometriosis symptoms

Instead of shutting down your hormones or removing tissue, what if you supported your body at the root?

A different approach to endometriosis symptoms

Oestra® is a prescription bioidentical hormone therapy compounded to rigorous U.S.
standards.

What’s inside — and how it’s made — matters.

Introducing Oestra®

Oestra® is a bioidentical hormone therapy.

Not birth control. Not surgery.
A root-cause hormone approach.

Oestra jar
  • Restore progesterone and estradiol
  • Reduce inflammation
  • Support the uterine lining
  • Help regulate your cycle
Our sources

Designed for
long-term confidence

Oestra® is a prescription bioidentical hormone therapy compounded to rigorous U.S. standards.

What’s inside — and how it’s made — matters.

The Result

What women with endometriosis
are experiencing

  • Less pelvic pain and cramping
  • Reduced bloating and inflammation
  • Lighter, more manageable periods
  • Better sleep and energy
  • Improved mood

Many women begin noticing changes within the first three months.

Oestra cream jar
Real people, real testimonials

Hear from 5000+ women

4.9/5

5,695 Reviews

I’ve lost weight, my energy is back, and my depression is gone...

MARCIA

VERIFIED PATIENT

The symptoms were just insane. I couldn’t explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It’s like I’m waking up from a foggy dream.

KIRALEE

VERIFIED PATIENT

Oestra has been a literal miracle for me. I suffered since age 12 with horrific periods and PMDD. It developed to end stage endometriosis by the time I was in my 20s.

I am blessed to say I am free from all endometriosis symptoms, no longer looking at any more surgery and free from PMDD!

HAYLEY

HAYLEY

VERIFIED PATIENT

I don’t know how to explain it but I feel like myself again. And that’s just unbelievable because I’ve tried so many things. I will be an Inner Balance customer for life.

STACEY

VERIFIED PATIENT

My doctor said I needed surgery. I tried Oestra first — and I’m so glad I did.

MARISSA

MARISSA

VERIFIED PATIENT

I knew I had a hormonal imbalance. I had anxiety, depression, really bad brain fog ... Oestra® has been a game changer for me. I’m so grateful to Inner Balance.

APRIL

APRIL

VERIFIED PATIENT

My ponytail has almost doubled at this point.

Nicole

VERIFIED PATIENT

I absolutely adore Inner Balance. I started it and I feel amazing. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it. You won’t regret it.

JESSICA

VERIFIED PATIENT

The key issue in endometriosis is
often low or ineffective progesterone

Oestra® supports your body by:

1

Restoring
progesterone levels

2

Helping your body
respond to it properly

3

Reducing inflammation
over time

Vaginal delivery allows better
absorption and more targeted effects.

Our science

How Oestra® supports your hormones

Oestra cream hormone absorption diagram

Progesterone

Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.

Progesterone

+

Estradiol

Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.

Estradiol

+

Ellagē® Base

Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.

Ellagē® Base

+

Clinical-grade care,
built into every plan.

$199 per month for your first 6 months

Then $99.50 per month ongoing

  • Prescription treatment

  • Free & fast shipping

  • Unlimited clinical follow-up

  • HSA/FSA Eligible

  • No insurance needed

  • Dose adjustments if needed

  • Cancel
    anytime

  • 20% off any supplement in FullScript

Your journey

Feel it week by week

Real changes. Backed by science. Felt by thousands of women.

Woman feeling well
Woman with Oestra cream
Oestra cream

Pain reduces

90% of women reported less pain, better overall mood, sleep, vaginal health, skin and lighter periods within 3 months.

Dr. Sarah Daccarett, MD — Founder & CEO, Inner Balance

Dr. Sarah Daccarett, MD

Founder & CEO, Inner Balance
Meet Dr. Sarah

Backed by science.
Formulated by women’s health experts.

Inner Balance was founded by Dr. Sarah Daccarett, MD, a board-certified specialist in women’s hormonal health and longevity medicine.

Her research has been published in leading medical journals, and she is licensed to practice medicine in 48 states.

“I founded Inner Balance because women deserve better
– better information, better care, and better outcomes.”
— Dr. Sarah Daccarett, MD

featured in

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LA Weekly logo — Inner Balance BodyMatched featured in LA Weekly
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Podcast network logo — Inner Balance BodyMatched women's health podcast feature
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Real guidance from the
doctor behind Oestra®

Dr. Sarah created Inner Balance to deliver a different kind of hormonal care.

Her approach centers on bioidentical hormone enrichment, safe delivery methods, and treatment guided by how women actually feel - not just lab numbers.

Traditional hormone therapy often targets a few symptoms like hot flashes or sleep. Oestra takes a broader approach, supporting brain function, metabolism, energy, skin, and overall wellbeing.

Vaginal delivery allows hormones to be absorbed directly into the bloodstream, supporting more stable levels and consistent symptom relief. Oral and topical methods are less efficient.

Estradiol and progesterone work together to support brain function, metabolism, skin, sleep, and overall balance. Using both creates a more complete and effective approach.

Oestra combines estradiol and progesterone into one daily treatment, replacing multiple prescriptions. This makes therapy easier to follow and more effective long term.

Most hormone therapy involves multiple prescriptions, labs, and long trial-and-error timelines. Oestra simplifies this into a streamlined, easier-to-follow approach.

Oestra uses bioidentical hormones identical to what the body produces. Treatment is monitored and adjusted, supporting safe, long-term use.

Many women notice early improvements in sleep and mood within weeks, with deeper changes like skin and cognitive function improving over 2–3 months.

Treatment begins with clinician review, followed by prescription delivery and ongoing adjustments based on how you feel, with continued clinical support.

Oestra supports natural hormone balance by allowing the body to convert progesterone into testosterone as needed, avoiding unnecessary side effects.

Oestra is a clinician-guided prescription therapy compounded in a licensed pharmacy and tailored to your symptoms.

Symptoms often reveal hormone imbalance more accurately than lab tests, which can appear normal despite real changes in how you feel.

Oestra was created after seeing consistent patterns of dismissed symptoms and overly complex care, with the goal of simplifying treatment and improving how women feel.

Hormonal changes begin earlier than most women expect. Starting support during perimenopause can help stabilize symptoms before they worsen.

How it works

Getting started is simple

Step 1

Complete our 2-minute health quiz

Help us understand your symptoms to see if
Oestra® suits you.

Step 2

Receive your
prescription treatment

Once approved, your meds
ship to your door. No visit needed.

Step 3

Start treatment and
get ongoing support

Our clinical care team is always here for you whenever you want to check in.

See If Oestra® Is Right for You

See If Oestra® Is Right for You

Free shipping. Cancel anytime. HSA/FSA Eligible.

You’re not managing this alone.

Every prescription is reviewed and monitored by a licensed clinician.

Hormones change. Your care adapts.

Unlimited
secured messaging

Unlimited secured messaging

Lab review and
dose adjustments if needed

Your action plan
Ongoing hormone monitoring dashboard

Ongoing monitoring
— not one-time prescribing.

Reclaim your body from endometriosis
fatigue
and pain.

Start here with Inner Balance.

See If Oestra® Is Right for You

No insurance needed. Cancel anytime.

Woman smiling

Questions?

TREATMENTS & SAFETY

Yes. Oestra® contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.

Yes. Hormone therapy is one of the most extensively studied treatments in medicine, with decades of research supporting its safety when used under medical supervision. Oestra® uses bioidentical estradiol and micronized progesterone — hormones identical to those naturally produced by your body — to support healthy hormone balance. If you ever choose to stop treatment, you can do so at any time. Your hormone levels will simply return to their natural baseline. Our medical team monitors your treatment and guides adjustments to ensure it remains safe and effective for you.

It goes beyond that. Oestra® is made by a 503B FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.

Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of personalized medicine with pharmaceutical-grade oversight.

Oestra® uses only bioidentical hormones—compounds identical to the ones your body used to make, derived from plant sources. In plain terms: they’re natural to your body, better tolerated than synthetics, and designed to restore—not override—your natural balance.

Two major ways:

– Delivery: Oestra® is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.

– Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.

Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra® gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.

No. Lab work is not required to begin treatment. Your care is guided first and foremost by your symptoms, medical history, and a comprehensive clinical review — not just lab numbers. Many hormone imbalances can be identified clinically, and you can begin treatment without testing. If you’d like deeper insight, we do offer convenient lab testing, and a full clinical review of your results is included in your care. Labs are optional — your journey with us will be personalized either way. You can start feeling better now, and add testing later if and when it makes sense for you.

No. In fact, Oestra® is designed to help correct estrogen dominance — not cause it. Estrogen dominance often occurs when progesterone levels are too low relative to estrogen. Oestra® provides both progesterone and estradiol in a carefully balanced ratio to help restore hormonal balance and calm the fluctuations that can drive symptoms. Because the hormones in Oestra® are delivered vaginally, they are absorbed efficiently and avoid the liver metabolism that can sometimes contribute to hormonal imbalances. This allows for more stable hormone levels and a more balanced response. Our medical team also personalizes dosing and monitors your progress to ensure your treatment remains balanced and effective for your body.

Most women tolerate Oestra® very well. As your body adjusts to hormone optimization, some women may experience mild breast tenderness or light cramping during the first few weeks. These symptoms are typically temporary and resolve quickly. Less common side effects may occur but are usually mild and easily addressed with simple adjustments to dosing or supportive recommendations. Our medical care team monitors your progress and is here to guide you every step of the way, ensuring your treatment remains comfortable, effective, and personalized to your needs.

No — Oestra® is non-contraceptive and does not suppress ovulation.

Yes. Bioidentical hormones are safe to take for decades and actually support longevity and disease prevention.

GETTING PRESCRIBED

Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a licensed clinician reviews your info, your prescription is sent to the pharmacy and shipped directly to you. You’ll receive a 3-month supply as part of a monthly subscription.

Yes. Every Oestra®prescription is reviewed and approved by a licensed clinician. You don’t need to book a separate appointment - your quiz responses help us determine if it’s safe to begin treatment and ensure you're a good candidate for our starting dose.

We don’t isolate hormones - we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra® is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.

PRODUCT USE

Apply one pearl-sized pump of cream daily to vaginal tissue using your finger. An applicator will be available in the future, but for now, we recommend manual application for best results.

You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra® isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.

Oestra® is delivered every 3 months, and billed monthly. Your membership includes treatment, pharmacy processing, shipping, and unlimited clinical support.

ELIGIBILITY & ACCESS

Not at all. We work with women as young as 21. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.

It’s not—because insurance typically only covers the most limited options. Oestra® replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. HSA/FSA is also accepted at checkout.

Yes, we accept HSA/FSA directly at checkout. Most carriers accept prescriptions as eligible and we also provide a letter of medical necessity.

SHIPPING & DELIVERY

Yes. Shipping is always free—every Oestra® prescription ships at no extra cost.

Most orders ship within 3 business days after your prescription is approved. We like to give your pharmacy time to prepare everything safely.

Yes. Your order arrives in plain pharmacy-labeled packaging, with no mention of hormones or Inner Balance on the outside. Inside, you’ll find your medication and a pharmacy insert with usage guidance.