Oestra™ for perimenopause
Find relief with our physician-formulated vaginal cream designed to address your symptoms through restoring hormonal balance.
Maintaining Quality & Excellence
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
More info
FDA announcement
The FDA's decision reflects updated research confirming that hormone therapy are both safe and beneficial.
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
PATIENT REPORTING
89%
90%
Suffering from perimenopause symptoms is now optional
Just a pearl-sized drop, once daily enriches your natural progesterone, estradiol and testosterone to put your body back in balance.
How Oestra™ enriches your hormones
The progesterone and estradiol in Oestra™ naturally restore optimal hormone levels while balancing testosterone production.
Just a pearl-sized drop, once daily enriches your natural progesterone, estradiol and testosterone to put your body back in balance.
Oestra™ consists of progesterone and estrogen. Why no testosterone?
Because your body naturally converts progesterone to testosterone.
Our customized treatment lets your body make its own. No need to supplement additional testosterone while on Oestra.
Invest in your best self
$199/month → first 6 months
Then just 50% off forever
From $99.50/mo
- 6 months money-back promise
- Cancel anytime
- Free shipping
- Unlimited clinical follow-up
- Personalized treatment plan
- HSA/FSA Eligible
Prescription-only product, prescribed by our board certified physicians. See one in 24-48 hrs. 90 day supply replenished every 90 days.
Natural whole body hormone enrichment with unbelievable benefits.
Most women begin to see improvements in 4 to 8 weeks. From period pain toenergy levels, Oestra™ helps reset your baseline for wellbeing.
Don’t just take our word for it.
Oestra™ helps women of all ages reclaim their energy, libido, sleep, and clarity. Every story is different—but the results speak for themselves.
Eliminate symptoms in just a few weeks.
Most women begin to see improvements in 4 to 8 weeks. From period pain to energy levels, Oestra™ helps reset your baseline for wellbeing.
Eliminate symptoms in just a few weeks.
Most women begin to see improvements in 4 to 8 weeks. From period pain to energy levels, Oestra™ helps reset your baseline for wellbeing.
Week 2
Feel the shift
Mood lifts, sleep deepens, and vaginal dryness begins to improve.
Week 4
Cycle reset
Periods become lighter and shorter. Brain fog fades, and energy returns.
Week 6
Glow up
Skin glows, hair thickens, and you’re feeling more like you. Time to check in with your clinician to assess if your dose needs adjusting.
Week 8
Begin to thrive
Metabolism fires up, libido increases, and your body starts working with you again.
Vaginal hormone delivery. Better absorption, fewer side effects.
Unlike pills or patches, Oestra™ is absorbed directly into the bloodstream, restoring your hormones to their optimal levels without compromising on absorption, safety, or efficacy.
Vaginal
Conventional treatments
Bypasses liver metabolism
Minimal side effects
Protects the uterus
Absorbs directly into bloodstream
Bioidentical Ingredients
Oestra™ is made with bioidentical estradiol and progesterone, these hormones help restore balance.
- Paraben-free
- Clinically-proven
- Plant-based
- Third party tested
- Allergen-free
- Fragrance-free
Progesterone
Micronized, plant-based, US-sourced and third party tested to ensure potency, purity & the highest quality.
Ellagē® Base
Ellagē® is pH-balanced and microbiome friendly, designed to protect and absorb through vaginal tissue.
Estradiol
Plant-based, US-sourced and third party tested to ensure potency, purity & the highest quality.
Designed by a Women’s Health Specialist
Dr. Sarah Daccarett spent over a decade treating hormone issues that mainstream medicine ignored. Oestra™ is the result—built to give women a safer, smarter, and more complete way to feel like themselves again.
Dr. Sarah Daccarett, MD Founder & CEO, Inner balance
“I founded Inner Balance because women deserve better – better information, better care, and better outcomes.”
— Dr, Sarah Daccarett
featured in
How to get started
Step 1Complete our
2-minute health quiz
Help us understand your symptoms to determine if Oestra™ is right for you.
Step 2Receive your
prescription treatment
Once approved, your meds ship to your door. No visit needed.
Step 3Start treatment and
get ongoing support
Our care team is always here for you whenever you want to check in.
Reviews
4.9/55,695 Reviews
Denise V. - Verified Buyer
Excellent!
This is the easiest way imaginable to dominate perimenopause. And by dominate, I mean forget it’s even happening.
Denise V. – Verified Buyer
Jenna R. - Verified Buyer
I’m back on track
I was feeling myself slipping away. After a few years of hopelessness, Oestra got me back on track during perimenopause. I have more energy, focus, and optimism about life.
Jenna R. – Verified Buyer
Lindsay M. - Verified Buyer
My libido is back!
Thanks to perimenopause, my libido was low and it was ruining my marriage – we would constantly fight over it. Turns out it wasn’t because I was tired, or tired of my husband. Once I started HRT my libido came back with a vengeance. Now my husband is the one who is tired.
Lindsay M. – Verified Buyer
FAQs
TREATMENT & SAFETY
Is Oestra™ safe to use?
Yes. Oestra™ uses FDA-approved bioidentical hormones, clinically proven to reduce symptoms and improve long-term health.
What are the side effects?
Some users experience breast tenderness or spotting in the early weeks. These are temporary and typically resolve on their own or with minor dosage adjustments.
Is Oestra™ bioidentical or synthetic?
Oestra™ is 100% bioidentical and plant-based—meaning it’s chemically identical to the hormones your body used to make.
How do you use Oestra™?
Apply a pearl-sized amount of the cream vaginally once a day. It absorbs quickly and gets to work fast—no pills, patches, or injections.
Do I need to be in menopause to take this?
No. Oestra™ is made specifically for women in perimenopause—even if you still get regular periods.
What if I was told I have estrogen dominance?
This is common in perimenopause. Oestra™ balances estrogen with progesterone and helps regulate your cycle.
Do I need lab work?
Nope. Lab tests are often misleading during perimenopause. We treat based on symptoms and adjust as needed.
Will this affect my ability to have kids?
No—Oestra™ is non-contraceptive and does not suppress ovulation.
Can I stay on this long-term?
Yes. Bioidentical hormones are safe to take for decades and actually support longevity and disease prevention.
GETTING PRESCRIBED
Do I need a prescription for Oestra™?
Yes. Our board-certified physicians prescribe a starting dose based on your clinical history provided in our health quiz.
How do I get started?
Take our 5-minute quiz. If you’re eligible, we’ll ship your prescription directly to your door and guide you through every step.
ACCOUNT, SUBSCRIPTIONS, & BILLING
Is Oestra™ covered by insurance?
Not currently. However, it’s often more cost-effective than managing multiple prescriptions, supplements, and appointments. plus, we offer a 6-month money-back guarantee.
If I don’t see results, can I get a refund?
Yes! We stand behind our product. If for any reason during the 6 months, you decide it’s not for you, you can simply request a full refund.
Do you accept HSA/FSA for payment?
While we don’t currently accept HSA/FSA on the website, you’re welcome to submit your monthly receipt to your HSA/FSA provider for potential reimbursement.
