Prescribed by licensed physician
Doctor visits included
HSA/FSA eligible
Money Back Guarantee on eligible products
4.9/5
Trusted by 100,000+ women
One daily cream with bioidentical estradiol and progesterone, designed to support steady hormone balance through perimenopause, menopause, and beyond.
Compounded by a U.S. licensed pharmacy
HSA/FSA eligible
Free shipping
See if Oestra® is right for you
Most women managing hormonal symptoms are combining supplements, OTC creams, and lifestyle adjustments - and still not feeling right.
Oestra® is a single daily application designed to support sleep, mood, energy, libido, skin, and metabolic health by addressing the hormonal root, not the individual symptoms.
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Every ingredient is there for a reason.
No fillers, no synthetic binders. Physician-formulated to maximize absorption and minimize side effects.
Oestra® is a single daily application designed to support sleep, mood, energy, libido, skin, and metabolic health by addressing the hormonal root, not the individual symptoms.
Check your eligibility
How a hormone enters your body determines how much of it actually reaches your bloodstream.
Oestra® is applied vaginally, allowing hormones to absorb directly into the bloodstream without first passing through the liver.
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We’ve helped thousands of women find their Inner Balance—starting with our widely-loved hormone enrichment cream, Oestra®.
4.9/5
5,695 Reviews
Testosterone isn't just a male hormone - women produce it too, and it declines alongside estrogen and progesterone from the 30s onward.
Oestra® supports testosterone indirectly: its bioidentical progesterone is a natural precursor that the body can convert to testosterone, helping bring low levels back toward a healthy range without overshoot or a separate prescription.
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No matter how consistently you eat, move, or sleep - hormones regulate how those efforts translate into results.
When estrogen and progesterone are low, metabolism, energy, muscle recovery, and mood all work harder for less return.
Oestra® is designed to support the hormonal foundation that makes everything else more effective.
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Oestra®is formulated by a women's health and longevity physician and compounded at an accredited U.S. 503A pharmacy - NABP, LegitScript, and PCAB certified.
Every batch is third-party tested for potency and purity before it ships.
Check your eligibility
Hormones are the foundation of healthy aging - not just a treatment for symptoms. They are the fountain of youth and the key to aging well.
See if Oestra® is right for you
Dr. Sarah Daccarett, MD
Founder & CEO, Inner Balance
4.9/5
5,695 Reviews
“I’ve lost weight, my energy is back, and my depression is gone...”
VERIFIED PATIENT
“The symptoms were just insane. I couldn’t explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It’s like I’m waking up from a foggy dream.”
VERIFIED PATIENT
“In the first couple days that I took it, I had 110% energy back. My husband was like ‘Whoa I haven’t seen this in you in a really long time.’ It just keeps getting better and better.”
VERIFIED PATIENT
“I can honestly say that after 3 days, I said to my husband... I don’t know how to explain it, but I feel myself again.”
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“I already feel a lot of my pain decreasing, I’m sleeping better, and I’m able to mentally focus.”
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“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”
VERIFIED PATIENT
“I absolutely adore Inner Balance. I started it and I feel amazing. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it. You won’t regret it.”
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Step 1
Help us understand your symptoms to see if Oestra® suits you.
Step 2
Once approved, your meds ship to your door. No visit needed.
Step 3
Our care team is always here for you whenever you want to check in.
See If Oestra® Is Right for You
Free shipping. Cancel anytime. HSA/FSA Eligible.
Every prescription is reviewed and monitored by a licensed clinician.
Hormones change. Your care adapts.
One cream. Two bioidentical hormones.
Hormone balance made simple.
See If Oestra® Is Right for You
No insurance needed. Cancel anytime.
TREATMENTS & SAFETY
Yes. Oestra® contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.
Yes. Hormone therapy is one of the most extensively studied treatments in medicine, with decades of research supporting its safety when used under medical supervision. Oestra® uses bioidentical estradiol and micronized progesterone — hormones identical to those naturally produced by your body — to support healthy hormone balance. If you ever choose to stop treatment, you can do so at any time. Your hormone levels will simply return to their natural baseline. Our medical team monitors your treatment and guides adjustments to ensure it remains safe and effective for you.
It goes beyond that. Oestra® is made by a 503B FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.
Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of personalized medicine with pharmaceutical-grade oversight.
Oestra® uses only bioidentical hormones—compounds identical to the ones your body used to make, derived from plant sources. In plain terms: they’re natural to your body, better tolerated than synthetics, and designed to restore—not override—your natural balance.
Two major ways:
– Delivery: Oestra® is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.
– Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.
Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra® gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.
No. Lab work is not required to begin treatment. Your care is guided first and foremost by your symptoms, medical history, and a comprehensive clinical review — not just lab numbers. Many hormone imbalances can be identified clinically, and you can begin treatment without testing. If you’d like deeper insight, we do offer convenient lab testing, and a full clinical review of your results is included in your care. Labs are optional — your journey with us will be personalized either way. You can start feeling better now, and add testing later if and when it makes sense for you.
No. In fact, Oestra® is designed to help correct estrogen dominance — not cause it. Estrogen dominance often occurs when progesterone levels are too low relative to estrogen. Oestra® provides both progesterone and estradiol in a carefully balanced ratio to help restore hormonal balance and calm the fluctuations that can drive symptoms. Because the hormones in Oestra® are delivered vaginally, they are absorbed efficiently and avoid the liver metabolism that can sometimes contribute to hormonal imbalances. This allows for more stable hormone levels and a more balanced response. Our medical team also personalizes dosing and monitors your progress to ensure your treatment remains balanced and effective for your body.
Most women tolerate Oestra® very well. As your body adjusts to hormone optimization, some women may experience mild breast tenderness or light cramping during the first few weeks. These symptoms are typically temporary and resolve quickly. Less common side effects may occur but are usually mild and easily addressed with simple adjustments to dosing or supportive recommendations. Our medical care team monitors your progress and is here to guide you every step of the way, ensuring your treatment remains comfortable, effective, and personalized to your needs.
No — Oestra® is non-contraceptive and does not suppress ovulation.
Yes. Bioidentical hormones are safe to take for decades and actually support longevity and disease prevention.
GETTING PRESCRIBED
Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a licensed clinician reviews your info, your prescription is sent to the pharmacy and shipped directly to you. You’ll receive a 3-month supply as part of a monthly subscription.
Yes. Every Oestra®prescription is reviewed and approved by a licensed clinician. You don’t need to book a separate appointment - your quiz responses help us determine if it’s safe to begin treatment and ensure you're a good candidate for our starting dose.
We don’t isolate hormones - we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra® is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.
PRODUCT USE
Apply one pearl-sized pump of cream daily to vaginal tissue using your finger. An applicator will be available in the future, but for now, we recommend manual application for best results.
You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra® isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.
Oestra® is delivered every 3 months, and billed monthly. Your membership includes treatment, pharmacy processing, shipping, and unlimited clinical support.
ELIGIBILITY & ACCESS
Not at all. We work with women as young as 18. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.
It’s not—because insurance typically only covers the most limited options. Oestra® replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. HSA/FSA is also accepted at checkout.
Yes, we accept HSA/FSA directly at checkout. Most carriers accept prescriptions as eligible and we also provide a letter of medical necessity.
SHIPPING & DELIVERY
Yes. Shipping is always free—every Oestra® prescription ships at no extra cost.
Most orders ship within 3 business days after your prescription is approved. We like to give your pharmacy time to prepare everything safely.
Yes. Your order arrives in discreet packaging. The outside of the box is labeled Inner Balance, but it does not identify the medication or indicate what’s inside.
