Thinking of starting hormones —
but still piecing it together?
Oestra® delivers bioidentical estradiol and progesterone in one balanced cream — designed for steady, full-body support.
No patch.
No progesterone pill.
No stacking prescriptions.
Just one daily application.
For women who want simpler, systemic hormone therapy — not more products.
HSA/FSA eligible
Compounded in a Licensed U.S. PharmacyMade in U.S.A
503A U.S. pharmacy. NABP, LegitScript & PCAB certified.
Clinician-Approved Prescription Treatment
HSA/FSA eligible. HIPAA-compliant & secure.
Bioidentical Estradiol + Micronized Progesterone
Clinically proven & third-party tested.
HSA/FSA eligible
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
More info
FDA announcement
The FDA's decision reflects updated research confirming that hormone therapy are both safe and beneficial.
Our Science
How Oestra® supports your hormones
Progesterone
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Ellagē® Base
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Bioidentical Progesterone
Protects the uterine lining, promotes restful sleep,balances estradiol, and supports a calm nervous system.
Bioidentical Progesterone
Hormone Support
Bioidentical progesterone for protection and balance
- Bioidentical
- uterine support
- CALMING SUPPORT
Ingredient Sourcing
- Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
- Third-party labs verify that the strength in the bottle matches the prescription on the label.
- Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Bioidentical Estriol
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Bioidentical Estriol
Hormone Support
Bioidentical estradiol — the body’s most active estrogen
- Bioidentical
- systemic effect
- plant-derived
Ingredient Sourcing
- Compounded using pharmaceutical-grade ingredients sourced from US manufacturers.
- Third-party labs verify that the strength in the bottle matches the prescription on the label.
- Our active ingredients arrive with a Certificate of Analysis to confirm 100% purity.
Ellage® Anhydrous Base
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Ellage® Anhydrous Base
Hormone Support
Ellage® anhydrous base for enhanced absorption
- anhydrous
- ph-balanced
- stable delivery
Why it matters
- 100% paraben-free, fragrance-free and contains no endocrine disruptors.
- Water-free and designed for sensitive vaginal tissue.
- Enhances absorption, prevents leakage, and maintains natural pH for consistent systemic hormone levels.
Supports Natural Testosterone
Progesterone serves as a precursor to testosterone, supporting libido, motivation, strength, and energy — naturally and without another product.
Supports Natural Testosterone
Hormone Support
Progesterone supports natural testosterone production
- NO SYNTHETIC TESTOSTERONE
- downstream conversion
- self-regulated
Why no added testosterone?
- Progesterone is a precursor to testosterone.
- Restoring it allows your body to regulate its own optimal levels — supporting libido, strength, and energy naturally.
Eliminate symptoms in just a few weeks
Estrogen is one of the most effective longevity interventions for women.
FDA announcement, November 2025
More info
FDA announcement
The FDA's decision reflects updated research confirming that hormone therapy are both safe and beneficial.
What Oestra® treats
Designed for the symptoms that actually disrupt your life
Oestra® supports:
- Clearer thinking and stable moods
- Deeper, more restorative sleep
- Healthier libido and sexual comfort
- Steadier energy and metabolism
- Bone and brain protection
- Vaginal health — without separate creams
This isn’t about chasing one symptom.
It’s about restoring steady hormone levels so your body can function normally again.
Stop managing your hormones like a to-do list
Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.
Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.
One formula.
One routine.
One price.
Most hormone therapy ends up looking like this:
The Other Methods
Estrogen patch,
progesterone pill
vaginal cream,
sometimes testosterone.
Real people, real testimonials
Hear from 5000+ women
Our Sources
Designed for long-term confidence
Oestra® is a prescription bioidentical hormone therapy compounded to rigorous U.S. standards.
What’s inside — and how it’s made — matters.
bioidentical estradiol & micronized progesterone
Molecularly identical to the hormones your body naturally produces.
Pharmaceutical-Grade
Active Ingredients
Sourced from FDA-inspected U.S. manufacturers. Compounded by a Licensed U.S. Pharmacy
third-party potency testing
Independent labs confirm the strength and accuracy of every compounded formula.
Clean, pH-Balanced Cream
Fragrance-free, paraben-free, and designed for optimal absorption.
Clinician-Guided Dosing
Dose increases are based on your symptoms and response. Treatment is guided by clinical evaluation and how you feel.
Simple, transparent pricing
$199 per month for your first 6 months
Then $99.50 per month ongoing
Prescription treatment
Free & fast shipping
Unlimited clinical follow-up
HSA/FSA Eligible
No insurance needed
Dose adjustments if needed
Cancel anytime
20% off any supplement in FullScript
The timeline
What most women notice
90%
of women reported better overall mood, sleep, vaginal health, skin and lighter periods within 2 months.
*Individual results vary. Based on internal data.Week 2
Improvement in vaginal health, mood and sleep
Week 4
More consistent energy and improved cycle stability
Week 6
Clearer thinking and reduced anxiety.
Week 8
Feeling more like yourself again.
“My brain fog just won’t lift.”
“My periods are heavier and unpredictable!”
“Why am I so anxious?”
“My mood swings are intense.”
“I’m exhausted no matter how much I sleep.”
The truth about testosterone
Do you need added testosterone?
Many women are told testosterone is the missing piece. But in many cases, low testosterone is a downstream effect of low progesterone and hormonal imbalance.
Oestra® does not contain added testosterone. Instead, it restores progesterone — which serves as a precursor hormone in your body’s natural testosterone pathway.
When hormone balance is restored, many women notice improvements in:
- Libido
- Motivation
- Energy
- Muscle tone
Without the risks often associated with testosterone creams, pellets, or injections.
For women who truly require additional testosterone, our clinicians can evaluate that separately. Balance first. Add only if necessary.
Vaginal doesn’t mean “local only”.
That means:
- Steadier levels
- Less estrone conversion
- Fewer side effects
Dr. Sarah Daccarett, MD Founder & CEO, Inner balance
Meet Dr. Sarah
Backed by science. Formulated by women’s health experts.
Inner Balance was founded by Dr. Sarah Daccarett, MD, a board-certified specialist in women’s hormonal health and longevity medicine.
Her research has been published in leading medical journals, and she is licensed to practice medicine in 50 states.
Hear from Dr Sarah
“I founded Inner Balance because women deserve better – better information, better care, and better outcomes.”
— Dr, Sarah Daccarett
featured in
Meet Dr. Sarah
Real guidance from the doctor behind Oestra®
Dr. Sarah created Inner Balance to deliver a different kind of hormonal care.
Her approach centers on bioidentical hormone enrichment, safe delivery methods, and treatment guided by how women actually feel – not just lab numbers.
Why I created Oestra
After treating thousands of women, a clear pattern emerged — anxiety, poor sleep, brain fog, and low energy, often dismissed despite “normal” labs. Existing hormone therapy felt fragmented and overly complex. Oestra was created to simplify care and actually address how women feel.
Why symptoms matter more than “normal” labs
Lab results don’t always reflect how hormones fluctuate in real life. Many women feel unwell despite being told everything is “normal.” Symptoms like brain fog, anxiety, and poor sleep are often more accurate indicators — and should guide treatment decisions.
What age can I start?
Hormonal changes often begin years before menopause, during perimenopause. Symptoms like anxiety, poor sleep, and low energy can appear even with normal labs. Starting support earlier can help stabilize these changes instead of waiting for symptoms to worsen.
Why Oestra® is different?
Traditional hormone therapy often targets a few symptoms like hot flashes or sleep. Oestra takes a broader approach, supporting brain function, metabolism, energy, skin, and overall wellbeing. It’s designed to help women feel fully balanced — not just manage isolated symptoms.
Why hormone therapy feels so complicated — and how we simplify it?
Hormone therapy is often fragmented into multiple prescriptions, lab tests, and trial-and-error adjustments that can take years. Oestra was designed to simplify the process into a single, streamlined approach that fits into your life without unnecessary complexity or cost.
Why simplicity matters in hormone therapy?
Oestra® combines estradiol and progesterone into a single daily treatment, replacing the need for multiple prescriptions. By simplifying the process, it becomes easier to stay consistent and see results. Sometimes the most effective solution is the simplest one.
Why estradiol and progesterone are combined?
Estradiol and progesterone work together to support the entire body — including brain health, metabolism, skin, sleep, and the nervous system. Using both helps restore balance more effectively than treating hormones in isolation.
Why Oestra uses vaginal delivery?
Vaginal delivery allows hormones to be absorbed directly into the bloodstream, supporting more stable levels and consistent symptom relief. Oral hormones are processed through the liver, and topical options have low absorption and risk transfer.
How long does it take to feel results?
Many women notice improvements in sleep, mood, and vaginal health within the first few weeks. Changes to skin, hair, and cognitive symptoms like brain fog typically take 2–3 months. Hormone balance builds over time.
What happens after you start Oestra®?
Your care begins with a clinician reviewing your assessment. Your prescription is compounded and shipped directly to you, with ongoing adjustments and access to clinical support as your needs evolve.
Is Oestra safe for long-term use?
Oestra uses bioidentical estradiol and micronized progesterone, identical to the body’s natural hormones. Treatment is monitored and adjusted over time, focusing on safe, long-term support.
Why Oestra® doesn’t include testosterone?
Oestra® restores progesterone, which the body can naturally convert into testosterone as needed. This supports balance without forcing levels and helps avoid side effects like acne, hair loss, or weight gain.
Is Oestra® a prescription treatment?
Oestra® is a prescription-based hormone therapy reviewed by a clinician and tailored to your symptoms. It’s compounded in a licensed pharmacy using pharmaceutical-grade ingredients.
How it works
Getting started is simple
What brings you to Inner Balance?
Select which most concerns you: *
- I have Polycystic Ovarian Syndrome (PCOS)
- Don’t really know, I just don’t feel great
- I am experiencing postpartum symptoms
- I have Endometriosis, or suspect that I do
Step 1Complete our 2-minute health quiz
Help us understand your symptoms to see if Oestra® suits you.
Shipped right
to your doorstep.
Step 2Receive your
prescription treatment
Once approved, your meds ship to your door. No visit needed.
Our promise is to deliver care that’s transparent, trustworthy, and centered around you.
Step 3Start treatment and
get ongoing support
Our clinical care team is always here for you whenever you want to check in.
You’re not managing this alone.
Hormones change. Your care adapts.
Unlimited
secured messaging
Lab review and
dose adjustments if needed
Smarter hormone therapy. Finally simplified.
One cream. Two bioidentical hormones.
Steady systemic support — without the patchwork.
See if Oestra® is a better fit for you.
No insurance needed. Cancel anytime.
Questions?
.
TREATMENTS & SAFETY
Is Oestra® safe to use?
Yes. Oestra® contains estradiol and progesterone—bioidentical hormones that are FDA-approved for use in treating hormone deficiency. It’s also delivered vaginally, a method backed by over 100 high-quality studies showing stable hormone levels, systemic benefits, and protection of the uterine lining. Safety isn’t just a promise—it’s clinically supported.
Is Oestra® safe to use long-term?
Yes. Hormone therapy is one of the most extensively studied treatments in medicine, with decades of research supporting its safety when used under medical supervision. Oestra® uses bioidentical estradiol and micronized progesterone — hormones identical to those naturally produced by your body — to support healthy hormone balance.
If you ever choose to stop treatment, you can do so at any time. Your hormone levels will simply return to their natural baseline.Our medical team monitors your treatment and guides adjustments to ensure it remains safe and effective for you.
Is Oestra® third-party tested?
It goes beyond that. Oestra® is made by a 503B FDA-regulated compounding pharmacy that’s inspected by the FDA, DEA, and state licensing boards. Every prescription batch undergoes rigorous potency, purity, and safety checks before it ever reaches your door.
Are compounding pharmacies safe?
Yes, when they’re held to the highest regulatory standards—as ours is. Our partner pharmacy is LegitScript-certified, meaning it meets stringent quality and safety criteria. You’re getting the best of personalized medicine with pharmaceutical-grade oversight.
Is Oestra® bioidentical or synthetic?
Oestra® uses only bioidentical hormones—compounds identical to the ones your body used to make, derived from plant sources. In plain terms: they’re natural to your body, better tolerated than synthetics, and designed to restore—not override—your natural balance.
How is Oestra® different from other hormone replacement therapies?
Two major ways:
– Delivery: Oestra® is a vaginal cream, allowing for faster absorption and more stable hormone levels than oral pills or topical patches.
– Formulation: It’s an all-in-one treatment. One pump a day delivers estradiol, progesterone, and testosterone (via conversion), saving you from juggling 4–6 separate prescriptions.
Does it work better than supplements?
Yes. Herbal supplements may temporarily ease symptoms, but they can’t restore hormone levels. Your body doesn’t make Dong Quai or Chaste Berry—it makes hormones. Oestra® gives your body what it actually needs, in the correct ratios, with prescription-level quality and precision.
Why don’t you require labs before starting?
No. Lab work is not required to begin treatment. Your care is guided first and foremost by your symptoms, medical history, and a comprehensive clinical review — not just lab numbers. Many hormone imbalances can be identified clinically, and you can begin treatment without testing.
If you’d like deeper insight, we do offer convenient lab testing, and a full clinical review of your results is included in your care. Labs are optional — your journey with us will be personalized either way. You can start feeling better now, and add testing later if and when it makes sense for you.
What if I was told I have estrogen dominance? Will this make it worse?
No. In fact, Oestra® is designed to help correct estrogen dominance — not cause it.
Estrogen dominance often occurs when progesterone levels are too low relative to estrogen. Oestra® provides both progesterone and estradiol in a carefully balanced ratio to help restore hormonal balance and calm the fluctuations that can drive symptoms.
Because the hormones in Oestra® are delivered vaginally, they are absorbed efficiently and avoid the liver metabolism that can sometimes contribute to hormonal imbalances. This allows for more stable hormone levels and a more balanced response.
Our medical team also personalizes dosing and monitors your progress to ensure your treatment remains balanced and effective for your body.
What are the side effects?
Most women tolerate Oestra® very well. As your body adjusts to hormone optimization, some women may experience mild breast tenderness or light cramping during the first few weeks. These symptoms are typically temporary and resolve quickly.
Less common side effects may occur but are usually mild and easily addressed with simple adjustments to dosing or supportive recommendations.
Our medical care team monitors your progress and is here to guide you every step of the way, ensuring your treatment remains comfortable, effective, and personalized to your needs.
Will this affect my ability to have kids?
No—Oestra® is non-contraceptive and does not suppress ovulation.
Can I stay on this long-term?
Yes. Bioidentical hormones are safe to take for decades and actually support longevity and disease prevention.
GETTING PRESCRIBED
How do I get started?
Start by taking our health quiz. If you’re a candidate, you’ll move straight to checkout. After a licensed clinician reviews your info, your prescription is sent to the pharmacy and shipped directly to you. You’ll receive a 3-month supply as part of a monthly subscription.
Do I need a prescription for Oestra®?
Yes. Every Oestra® prescription is reviewed and approved by a licensed clinician. You don’t need to book a separate appointment – your quiz responses help us determine if it’s safe to begin treatment and ensure you’re a good candidate for our starting dose.
How is Inner Balance’s approach to HRT different?
We don’t isolate hormones – we balance them. Most HRT programs target estrogen, progesterone, or testosterone in isolation. Oestra® is different. It supports all three hormones together in the right ratios, to restore balance without the usual trial-and-error or side effects.
PRODUCT USE
How do you use Oestra®?
Apply one pearl-sized pump of cream daily to vaginal tissue using your finger. An applicator will be available in the future, but for now, we recommend manual application for best results.
How long does Oestra® take to work?
You may start noticing changes within the first 2–4 weeks—especially around mood, sleep, and vaginal dryness. Deeper shifts like energy, skin, and metabolism take longer, often 3–6 months or more. Oestra® isn’t a quick fix; it’s a full-body recalibration. But when balance returns, it’s worth the wait.
How often is Oestra® sent?
Oestra® is delivered every 3 months, and billed monthly. Your membership includes treatment, pharmacy processing, shipping, and unlimited clinical support.
ELIGIBILITY & ACCESS
Do you have to be in menopause to start Oestra®?
Not at all. We work with women as young as 21. In fact, many women start in their 30s or 40s—often before traditional medicine recognizes hormone decline. The earlier you begin, the more protection you provide your bones, brain, heart, skin, and metabolism.
Is Oestra® covered by insurance?
It’s not—because insurance typically only covers the most limited options. Oestra® replaces 5–6 prescriptions and is still more cost-effective than most HRT plans. HSA/FSA is also accepted at checkout.
Do you accept HSA/FSA for payment?
Yes, we accept HSA/FSA directly at checkout. Most carriers accept prescriptions as eligible and we also provide a letter of medical necessity.
SHIPPING & DELIVERY
Do you offer free shipping?
Yes. Shipping is always free—every Oestra® prescription ships at no extra cost.
When will my order ship?
Most orders ship within 3 business days after your prescription is approved. We like to give your pharmacy time to prepare everything safely.
Is the packaging discreet?
Yes. Your order arrives in plain pharmacy-labeled packaging, with no mention of hormones or Inner Balance on the outside. Inside, you’ll find your medication and a pharmacy insert with usage guidance.
