Clinically Crafted. Quality Assured.
Certified
Certified
Certified
4.9/5
5,695 Reviews
A prescription treatment with bioidentical estradiol and progesterone that delivers whole-body results.
Oestra® is a daily vaginal cream with bioidentical estrogen and progesterone. It restores whole-body hormone balance to improve sleep, mood, libido, and more — with better absorption and fewer side effects than pills or patches.
From $99.50/mo
Cancel anytime
Free shipping
6 months money-back guarantee
HSA/FSA Eligible
Prescription treatment
Unlimited access to healthcare experts
Clinically Crafted. Quality Assured.
Certified
Certified
Certified
Certified
Certified
Certified
Per pump: 3 mg estradiol + 100 mg micronized progesterone- Bioidentical hormones identical to what your body naturally produces, supporting balanced, steady levels- Delivered in a clean, pH-balanced cream base (MCT oil, hydrogenated vegan fat, glycerol monostearate, propoxyl stearate, ricinoleate, poloxamer 407, cetearyl ether) for consistent absorption
- Smarter absorption through vaginal delivery- Hormones are absorbed directly into the bloodstream - bypassing the liver for more stable levels- Higher absorption: ~100% vs. oral (10–20%) or topical (3–20%)The result: more consistent hormone levels and more reliable symptom support
- Body-matched formulation. Optimal estrogen-to-progesterone ratio to mimic the body’s natural state.- Whole-body treatment. Not just for vaginal dryness — Oestra® supports mood, energy, sleep, metabolism, and more.- Support whenever you need it. You’ll be guided by clinical experts who listen, adjust, and support every step of the way.- Made for women by women. Founded by Dr. Sarah Daccarett, MD, after her own hormone journey.
*Prescription-only product, prescribed by our board certified physicians.
90 day supply replenished every 90 days.
Measured improvements in just a few weeks
In a 6-month outcomes review of women using Oestra®:
0%
improved vaginal dryness
0%
improved sleep quality
0%
improved mood
0%
sharper focus and vitality
0%
improved energy levels
These changes reflect restored hormone levels — not temporary symptom masking.
Simple, transparent pricing
$199 per month for your first 6 months
Then $99.50 per month ongoing
Prescription treatment
Free & fast shipping
Unlimited clinical follow-up
HSA/FSA Eligible
No insurance neededNo insurance needed,
cancel anytimeDose adjustments
if needed6-month money back
guarantee20% off any supplement
in FullScript
What most women notice
Week 2
Improvement in vaginal health,
mood and sleep
Week 4
More consistent energy and
improved cycle stability
Week 6
Clearer thinking and
reduced anxiety.
Week 8
Feeling more like yourself again.
of women reported better overall mood, sleep, vaginal health, skin and lighter periods within 3 months.
*Individual results vary. Based on internal data.
Hear from 5000+ women
4.9/5
5,695 Reviews
“I’ve lost weight, my energy is back, and my depression is gone...”
MARCIA
VERIFIED PATIENT
“The symptoms were just insane. I couldn’t explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It’s like I’m waking up from a foggy dream.”
KIRALEE
VERIFIED PATIENT
“In the first couple days that I took it, I had 110% energy back. My husband was like ‘Whoa I haven’t seen this in you in a really long time.’ It just keeps getting better and better.”
HAYLEY
VERIFIED PATIENT
“I can honestly say that after 3 days, I said to my husband... I don’t know how to explain it, but I feel myself again.”
STACEY
VERIFIED PATIENT
“I already feel a lot of my pain decreasing, I’m sleeping better, and I’m able to mentally focus.”
ELANA
VERIFIED PATIENT
“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”
MEGAN
VERIFIED PATIENT
“I absolutely adore Inner Balance. I started it and I feel amazing. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it. You won’t regret it.”
JESSICA
VERIFIED PATIENT
Stop managing your hormones like a to-do list
Oestra® replaces the patchwork with
one steady formula designed for
systemic absorption and balanced dosing.
One formula.
One routine.
One price.That rhythm matters.
The Other Methods
Most hormone therapy ends up
looking like this:
Estrogen patch
Progesterone pill
Vaginal cream
Sometimes testosterone
But it’s fragmented.
Oestra® replaces the patchwork with
one steady formula designed for
systemic absorption and balanced dosing.
One formula.
One routine.
One price.That rhythm matters.
The Other Methods
Most hormone therapy ends up
looking like this:
Estrogen patch
Progesterone pill
Vaginal cream
Sometimes testosterone
But it’s fragmented.
Oestra® replaces the patchwork with
one steady formula designed for
systemic absorption and balanced dosing.
One formula.
One routine.
One price.That rhythm matters.
The Other Methods
Most hormone therapy ends up
looking like this:
Estrogen patch
Progesterone pill
Vaginal cream
Sometimes testosterone
But it’s fragmented.
How Oestra® supports
your hormones
Progesterone
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Progesterone
Estradiol
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Estradiol
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Ellagē® Base
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Ellagē® Base
Ellagē® Base
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Ellagē® Base
Bioidentical
Progesterone
Protects the uterine lining,
promotes restful sleep,
balances estradiol, and
supports a calm nervous system.
Bioidentical
Estradiol
Supports brain, bones, metabolism,
mood, vaginal tissue, and long-term
vitality.
Ellage®
Anhydrous Base
Engineered for vaginal absorption to
enhance bioavailability, maintain natural
pH, prevent leakage, and deliver stable
systemic hormone levels.
Supports Natural
Testosterone
Progesterone serves as a precursor to
testosterone, supporting libido,
motivation, strength, and energy —
naturally and without another product.
Bioidentical
Progesterone
Protects the uterine lining,
promotes restful sleep,
balances estradiol, and
supports a calm nervous system.
Bioidentical
Estradiol
Supports brain, bones, metabolism,
mood, vaginal tissue, and long-term
vitality.
Ellage®
Anhydrous Base
Engineered for vaginal absorption to
enhance bioavailability, maintain natural
pH, prevent leakage, and deliver stable
systemic hormone levels.
Supports Natural
Testosterone
Progesterone serves as a precursor to
testosterone, supporting libido,
motivation, strength, and energy —
naturally and without another product.
Why delivery method matters
How estrogen enters the body determines how well it works.
Treatment
Liver metabolism
Dose required
Hormone levels
Side effects
Targeted support
Oestra® (Vaginal)
Bypasses liver
Lower, more efficient
Steadier absorption
Lower systemic burden
Direct + systemic benefit
Oral
Processed by liver
Higher due to breakdown
Peaks & Crashes
Higher nausea & clotting markers
Systemic only
Patch
Bypasses liver
Moderate
Can fluctuate with skin factors
Possible skin irritation
Systemic only
Oestra® works with your physiology —
not against it.
No digestive breakdown. No first-pass liver metabolism.
Just efficient, steady estrogen support where it matters most.
take the 2-min quiz
Backed by science.
Formulated by women’s health experts.
Inner Balance was founded by Dr. Sarah Daccarett, MD, a board-certified specialist in women’s hormonal health and longevity medicine.
Her research has been published in leading medical journals, and she is licensed to practice medicine in 50 states.
Hear from Dr Sarah
“I founded Inner Balance because women deserve better
– better information, better care, and better outcomes.”
featured in
Real guidance from the
doctor behind Oestra®
Dr. Sarah created Inner Balance to deliver a different kind of hormonal care.
Her approach centers on bioidentical hormone enrichment, safe delivery methods, and treatment guided by how women actually feel - not just lab numbers.
Traditional hormone therapy often targets a few symptoms like hot flashes or sleep. Oestra takes a broader approach, supporting brain function, metabolism, energy, skin, and overall wellbeing.
Vaginal delivery allows hormones to be absorbed directly into the bloodstream, supporting more stable levels and consistent symptom relief. Oral and topical methods are less efficient.
Estradiol and progesterone work together to support brain function, metabolism, skin, sleep, and overall balance. Using both creates a more complete and effective approach.
Oestra combines estradiol and progesterone into one daily treatment, replacing multiple prescriptions. This makes therapy easier to follow and more effective long term.
Most hormone therapy involves multiple prescriptions, labs, and long trial-and-error timelines. Oestra simplifies this into a streamlined, easier-to-follow approach.
Oestra uses bioidentical hormones identical to what the body produces. Treatment is monitored and adjusted, supporting safe, long-term use.
Many women notice early improvements in sleep and mood within weeks, with deeper changes like skin and cognitive function improving over 2–3 months.
Treatment begins with clinician review, followed by prescription delivery and ongoing adjustments based on how you feel, with continued clinical support.
Oestra supports natural hormone balance by allowing the body to convert progesterone into testosterone as needed, avoiding unnecessary side effects.
Oestra is a clinician-guided prescription therapy compounded in a licensed pharmacy and tailored to your symptoms.
Symptoms often reveal hormone imbalance more accurately than lab tests, which can appear normal despite real changes in how you feel.
Oestra was created after seeing consistent patterns of dismissed symptoms and overly complex care, with the goal of simplifying treatment and improving how women feel.
Hormonal changes begin earlier than most women expect. Starting support during perimenopause can help stabilize symptoms before they worsen.
Getting started is simple
Step 1
Complete our 2-minute health quiz
Help us understand your symptoms to see if Oestra® suits you.
Step 2
Receive your prescription treatment
Once approved, your meds ship to your door. No visit needed.
Step 3
Start treatment and get ongoing support
Our care team is always here for you whenever you want to check in.
See If Oestra® Is Right for You
Free shipping. Cancel anytime. HSA/FSA Eligible.
I finally feel like myself again
Oestra® helps women of all ages reclaim their energy, libido, sleep, and clarity.
Every story is different — but the results speak for themselves.
4.9/5
5,695 Reviews
Take the quiz
You’re not managing this alone
Every prescription is reviewed and monitored by a licensed clinician.
Hormones change. Your care adapts.
Unlimited
secured messaging
Lab review and
dose adjustments if needed
Ongoing monitoring
— not one-time prescribing.
6–month money
back promise
We’re so confident you’ll love it that we give an industry-leading full refund guarantee.
See If Oestra® Is Right for You
No insurance needed. Cancel anytime.
Questions?
Getting Started
The first thing to do is to take our health quiz, where we will make sure you are a candidate for Oestra. From there, you’ll checkout. Once our team of experts confirm you’re good to go, we’ll send your prescription to our pharmacy, and they will ship directly to you.
No. Lab tests fluctuate and don't tell the whole story. If you’re experiencing symptoms, that’s the signal. We focus on how you feel—not just what your labs say.
Yes. After you complete the health quiz, a board-certified physician reviews your clinical history to determine if Oestra® is right for you. If approved, your prescription is filled and shipped to your door.
Most other HRTs focus on hormone levels individually. We take a more comprehensive approach, focusing on the ratios of estrogen, progesterone, and testosterone to bring them into balance—addressing the full spectrum of symptoms more effectively.
Yes. You have 6 full months to decide if Oestra® is right for you. If you're not seeing results, we’ll refund you—no questions asked.
Safety & Ingredients
Yes. Estradiol and progesterone are FDA-approved for treatment because they have been tested for safety and efficacy. Extensive research—including 100+ high-quality trials and large-scale observational studies—demonstrates their safety and benefits. There are also 200+ studies on vaginal administration showing protection of the endometrial lining.
Yes, it is absolutely safe. In fact, increasing estrogen in perimenopause can protect against heart disease, increase bone strength, and support overall vitality—beyond improving brain fog, vaginal dryness, and hot flashes.
Yes. All 503B compounding pharmacies (including ours) follow rigorous third-party testing and are regulated by the FDA, DEA, and state boards. Medications undergo potency, sterility, and quality checks before shipment.
Yes. Oestra® is compounded in a 503B FDA-regulated pharmacy that is also DEA-inspected and LegitScript certified. Each batch is tested for potency, purity, sterility, and consistency before shipping.