Based on your answers,
Oestra® is a strong fit for you.

HSA/FSA eligible for reimbursement

Oestra™
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Trusted by 60,000+ women

Oestra® combines bioidentical estradiol and progesterone in one treatment designed to support steady balance, daily.

Why Women
Choose Oestra®

The FDA’s decision reflects updated research confirming that hormone therapy are both safe and beneficial.

Oestra® isn’t just for one symptom — it supports your whole body from the inside out. Unlike traditional low dose estradiol vaginal creams, that are designed to stay local and treat vaginal dryness only - Oestra® is an appropriate dose and therefore absorbs systemically.By replenishing bio-identical estrogen and progesterone, and balancing testosterone, in the right ratio, it addresses the root cause of hormonal imbalance, not just local issues.That means better sleep, calmer moods, glowing skin, thicker hair, clearer mind, lighter periods, and real improvements in energy, metabolism, libido, and vaginal health. All from one product.

Since Oestra® is delivered vaginally — it gives you powerful, systemic results with far fewer side effects because it avoids the liver. No grogginess, no digestion issues, no toxic liver metabolites.Just bioidentical hormones your body recognizes and uses efficiently. Plus, no contamination risk to partners or kids like with skin creams. And since it reaches the uterine lining, where it’s needed, it offers protection that topicals often miss.

No injections. No sticker marks. No labs. No juggling 5 different HRT products. Oestra® is designed to be applied vaginally, gently inside the opening or underside of the labia.Just once-daily, with a pearl-sized amount of cream in just 10 seconds - That’s all it takes to start feeling real changes — no complicated routines or exhausting regimens. Just one simple step to feel better, look better, and live better.

Woman with Oestra creamWoman with Oestra cream

Clinically guided.
Scientifically proven.

  • Bioidentical Hormones

    Bioidentical Hormones

  • Clinician Prescribed

    Clinician Prescribed

  • Compounded in a Licensed U.S. Pharmacy

    Compounded in a Licensed U.S. Pharmacy

  • Clinician Follow-up Included

    Clinician Follow-up Included

  • 6-Months Money Back Guarantee

    6-Months Money Back Guarantee

  • Cancel anytime

    Cancel anytime

Start my treatment plan

Oestra creamOestra cream

Why Oestra® was recommended

Based on your responses, you reported symptoms commonly linked to hormonal shifts.

These may include:

  • Sleep disruption

  • Anxiety or mood changes

  • Brain fog or difficulty focusing

  • Changes in libido or vaginal health

  • Low energy or weight gain

  • Skin or hair changes

Hormones play a critical role in how your body regulates mood, energy, metabolism, and cognitive function.

Oestra® helps support balanced hormone levels through a consistent daily protocol designed for whole-body hormonal health.

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Your recommended treatment

Oestra cream

4.9/5

5,695 Reviews

Oestra® Hormone Therapy

Bioidentical Estradiol +
Micronized Progesterone
Once-daily vaginal cream designed for systemic absorption.

Oestra® supports:

Mental clarity & moodMental clarity & mood

Mental clarity & mood

Energy & sleepEnergy & sleep

Energy & sleep

Libido & sexual wellnessLibido & sexual wellness

Libido & sexual wellness

Cycle & hormonal harmonyCycle & hormonal harmony

Cycle & hormonal harmony

One balanced formula.
One simple daily routine

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How Oestra® supports
your hormones

Cream

Progesterone

Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.

Progesterone

+

Estradiol

Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.

Estradiol

+

Ellagē® Base

Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.

Ellagē® Base

+

Bioidentical
Progesterone

Protects the uterine lining,
promotes restful sleep,
balances estradiol, and
supports a calm nervous system.

Bioidentical
Estradiol

Supports brain, bones,
metabolism, mood,
vaginal tissue, and long-term vitality.

Ellage®
Anhydrous Base

Engineered for vaginal
absorption to enhance
bioavailability, maintain natural
pH, prevent leakage, and deliver
stable systemic hormone levels.

Supports Natural
Testosterone

Progesterone serves as a precursor to testosterone, supporting libido, motivation, strength, and energy — naturally and without another product.

Hear from
5000+ women

Oestra® helps women of all ages reclaim their energy, libido, sleep, and clarity. Every story is different — but the results speak for themselves.

“I’ve lost weight, my energy is back, and my depression is gone...”

MARCIA

VERIFIED PATIENT

“The symptoms were just insane. I couldn’t explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It’s like I’m waking up from a foggy dream.”

KIRALEE

VERIFIED PATIENT

“In the first couple days that I took it, I had 110% energy back. My husband was like ‘Whoa I haven’t seen this in you in a really long time.’ It just keeps getting better and better.”

HAYLEY

HAYLEY

VERIFIED PATIENT

“I can honestly say that after 3 days, I said to my husband... I don’t know how to explain it, but I feel myself again.”

STACEY

VERIFIED PATIENT

“I already feel a lot of my pain decreasing, I’m sleeping better, and I’m able to mentally focus.”

ELANA

ELANA

VERIFIED PATIENT

“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”

MEGAN

MEGAN

VERIFIED PATIENT

“I absolutely adore Inner Balance. I started it and I feel amazing. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it. You won’t regret it.”

JESSICA

VERIFIED PATIENT

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Simple, transparent pricing

$199 per /month for your first 6 months

Then $99.50 per month

  • Prescription treatment

  • Free & fast
    shipping

  • Unlimited clinical
    follow-up

  • HSA/FSA Eligible

  • No insurance needed, cancel anytime

  • Dose adjustments if needed*

  • 6-month
    money back guarantee

  • 20% off any supplement in FullScript

*Dose adjustments may incur an additional cost.

Hormone support, simplified

Oestra cream

Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.

  • One formula.

  • One routine.

  • One price.

Other methods
Other methods

The Other Methods

Most hormone therapy
ends up looking like this:

  • Estrogen patch

  • Progesterone pill

  • Vaginal cream

  • Sometimes testosterone

Oestra cream

Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.

  • One formula.

  • One routine.

  • One price.

Other methods
Other methods

The Other Methods

Most hormone therapy
ends up looking like this:

  • Estrogen patch

  • Progesterone pill

  • Vaginal cream

  • Sometimes testosterone

You’re not managing
this alone

Every prescription is reviewed and monitored by a licensed clinician.

Hormones change. Your care adapts.

Unlimited
secured messaging

Unlimited secured messagingUnlimited secured messaging

Lab review and
dose adjustments if needed

Lab review and dose adjustments if neededLab review and dose adjustments if needed

Ongoing monitoring
— not one-time prescribing.

Ongoing monitoring — not one-time prescribing.Ongoing monitoring — not one-time prescribing.

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What most women notice

Real changes. Backed by science.
Felt by thousands of women.

Oestra hormone progress timeline by week 2
Oestra hormone progress timeline by week 2

90%

of women reported better overall mood, sleep, vaginal health, skin and lighter periods.

*Individual results vary. Based on internal data.

Oestra hormone progress timeline by week 4
Oestra hormone progress timeline by week 4

98%

of women said they had lighter and less painful periods, and resolved vaginal dryness.

Oestra hormone progress timeline by week 6
Oestra hormone progress timeline by week 6

80%

shared that Oestra® improved their sleep and mental health.

Improvement in vaginal health,
mood and sleep

Early changes in comfort, sleep quality and emotional balance.

90% of women reported better overall mood, sleep, vaginal health, skin and lighter periods.

FAQs

Getting Started

The first thing to do is to take our health quiz, where we will make sure you are a candidate for Oestra. From there, you’ll checkout. Once our team of experts confirm you’re good to go, we’ll send your prescription to our pharmacy, and they will ship directly to you.

No. Lab tests fluctuate and don't tell the whole story. If you’re experiencing symptoms, that’s the signal. We focus on how you feel—not just what your labs say.

Yes. After you complete the health quiz, a board-certified physician reviews your clinical history to determine if Oestra® is right for you. If approved, your prescription is filled and shipped to your door.

Most other HRTs focus on hormone levels individually. We take a more comprehensive approach, focusing on the ratios of estrogen, progesterone, and testosterone to bring them into balance—addressing the full spectrum of symptoms more effectively.

Yes. You have 6 full months to decide if Oestra® is right for you. If you're not seeing results, we’ll refund you—no questions asked.

Safety & Ingredients

Yes. Estradiol and progesterone are FDA-approved for treatment because they have been tested for safety and efficacy. Extensive research—including 100+ high-quality trials and large-scale observational studies—demonstrates their safety and benefits. There are also 200+ studies on vaginal administration showing protection of the endometrial lining.

Yes, it is absolutely safe. In fact, increasing estrogen in perimenopause can protect against heart disease, increase bone strength, and support overall vitality—beyond improving brain fog, vaginal dryness, and hot flashes.

Yes. All 503B compounding pharmacies (including ours) follow rigorous third-party testing and are regulated by the FDA, DEA, and state boards. Medications undergo potency, sterility, and quality checks before shipment.

Yes. Oestra® is compounded in a 503B FDA-regulated pharmacy that is also DEA-inspected and LegitScript certified. Each batch is tested for potency, purity, sterility, and consistency before shipping.

Disclaimer: Oestra® is a compounded prescription medication prepared by a licensed U.S. pharmacy.
Compounded medications are not evaluated or approved by the FDA but are regulated under federal and state pharmacy laws and prescribed on an individual basis.

Woman with Oestra
Woman with Oestra

Hormone therapy doesn’t
have to be complicated

One physician-formulated cream.
Two bioidentical hormones.

A steady daily routine designed to
support your body long-term

Start your treatment plan

No insurance needed. Cancel anytime.