HSA/FSA eligible for reimbursement






Trusted by 60,000+ women
Oestra® combines bioidentical estradiol and progesterone in one treatment designed to support steady balance, daily.
The FDA’s decision reflects updated research confirming that hormone therapy are both safe and beneficial.
Oestra® isn’t just for one symptom — it supports your whole body from the inside out. Unlike traditional low dose estradiol vaginal creams, that are designed to stay local and treat vaginal dryness only - Oestra® is an appropriate dose and therefore absorbs systemically.By replenishing bio-identical estrogen and progesterone, and balancing testosterone, in the right ratio, it addresses the root cause of hormonal imbalance, not just local issues.That means better sleep, calmer moods, glowing skin, thicker hair, clearer mind, lighter periods, and real improvements in energy, metabolism, libido, and vaginal health. All from one product.
Since Oestra® is delivered vaginally — it gives you powerful, systemic results with far fewer side effects because it avoids the liver. No grogginess, no digestion issues, no toxic liver metabolites.Just bioidentical hormones your body recognizes and uses efficiently. Plus, no contamination risk to partners or kids like with skin creams. And since it reaches the uterine lining, where it’s needed, it offers protection that topicals often miss.
No injections. No sticker marks. No labs. No juggling 5 different HRT products. Oestra® is designed to be applied vaginally, gently inside the opening or underside of the labia.Just once-daily, with a pearl-sized amount of cream in just 10 seconds - That’s all it takes to start feeling real changes — no complicated routines or exhausting regimens. Just one simple step to feel better, look better, and live better.



Bioidentical Hormones

Clinician Prescribed

Compounded in a Licensed U.S. Pharmacy

Clinician Follow-up Included

6-Months Money Back Guarantee

Cancel anytime
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Based on your responses, you reported symptoms commonly linked to hormonal shifts.
These may include:
Sleep disruption
Anxiety or mood changes
Brain fog or difficulty focusing
Changes in libido or vaginal health
Low energy or weight gain
Skin or hair changes
Hormones play a critical role in how your body regulates mood, energy, metabolism, and cognitive function.
Oestra® helps support balanced hormone levels through a consistent daily protocol designed for whole-body hormonal health.
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4.9/5
5,695 Reviews
Oestra® Hormone Therapy
Bioidentical Estradiol +
Micronized Progesterone
Once-daily vaginal cream designed for systemic absorption.








One balanced formula.
One simple daily routine
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Progesterone
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Progesterone
Estradiol
Engineered for vaginal absorption to enhance bioavailability, maintain natural pH, prevent leakage, and deliver stable systemic hormone levels.
Estradiol
Ellagē® Base
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Ellagē® Base

Protects the uterine lining,
promotes restful sleep,
balances estradiol, and
supports a calm nervous system.

Supports brain, bones,
metabolism, mood,
vaginal tissue, and long-term vitality.

Engineered for vaginal
absorption to enhance
bioavailability, maintain natural
pH, prevent leakage, and deliver
stable systemic hormone levels.

Progesterone serves as a precursor to testosterone, supporting libido, motivation, strength, and energy — naturally and without another product.
Oestra® helps women of all ages reclaim their energy, libido, sleep, and clarity. Every story is different — but the results speak for themselves.
“I’ve lost weight, my energy is back, and my depression is gone...”
VERIFIED PATIENT
“The symptoms were just insane. I couldn’t explain them, there was no reason for them. Fast forward... I finally found Inner Balance. It’s like I’m waking up from a foggy dream.”
VERIFIED PATIENT
“In the first couple days that I took it, I had 110% energy back. My husband was like ‘Whoa I haven’t seen this in you in a really long time.’ It just keeps getting better and better.”
VERIFIED PATIENT
“I can honestly say that after 3 days, I said to my husband... I don’t know how to explain it, but I feel myself again.”
VERIFIED PATIENT
“I already feel a lot of my pain decreasing, I’m sleeping better, and I’m able to mentally focus.”
VERIFIED PATIENT
“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”
VERIFIED PATIENT
“I absolutely adore Inner Balance. I started it and I feel amazing. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it. You won’t regret it.”
VERIFIED PATIENT


Prescription treatment
Free & fast
shipping
Unlimited clinical
follow-up
HSA/FSA Eligible
No insurance needed, cancel anytime
Dose adjustments if needed*
6-month
money back guarantee
20% off any supplement in FullScript
*Dose adjustments may incur an additional cost.

Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.
One formula.
One routine.
One price.

Most hormone therapy
ends up looking like this:
Estrogen patch
Progesterone pill
Vaginal cream
Sometimes testosterone

Oestra® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.
One formula.
One routine.
One price.

Most hormone therapy
ends up looking like this:
Estrogen patch
Progesterone pill
Vaginal cream
Sometimes testosterone
Every prescription is reviewed and monitored by a licensed clinician.
Hormones change. Your care adapts.






Real changes. Backed by science.
Felt by thousands of women.
90%
of women reported better overall mood, sleep, vaginal health, skin and lighter periods.
*Individual results vary. Based on internal data.
98%
of women said they had lighter and less painful periods, and resolved vaginal dryness.
80%
shared that Oestra® improved their sleep and mental health.
90% of women reported better overall mood, sleep, vaginal health, skin and lighter periods.
Getting Started
The first thing to do is to take our health quiz, where we will make sure you are a candidate for Oestra. From there, you’ll checkout. Once our team of experts confirm you’re good to go, we’ll send your prescription to our pharmacy, and they will ship directly to you.
No. Lab tests fluctuate and don't tell the whole story. If you’re experiencing symptoms, that’s the signal. We focus on how you feel—not just what your labs say.
Yes. After you complete the health quiz, a board-certified physician reviews your clinical history to determine if Oestra® is right for you. If approved, your prescription is filled and shipped to your door.
Most other HRTs focus on hormone levels individually. We take a more comprehensive approach, focusing on the ratios of estrogen, progesterone, and testosterone to bring them into balance—addressing the full spectrum of symptoms more effectively.
Yes. You have 6 full months to decide if Oestra® is right for you. If you're not seeing results, we’ll refund you—no questions asked.
Safety & Ingredients
Yes. Estradiol and progesterone are FDA-approved for treatment because they have been tested for safety and efficacy. Extensive research—including 100+ high-quality trials and large-scale observational studies—demonstrates their safety and benefits. There are also 200+ studies on vaginal administration showing protection of the endometrial lining.
Yes, it is absolutely safe. In fact, increasing estrogen in perimenopause can protect against heart disease, increase bone strength, and support overall vitality—beyond improving brain fog, vaginal dryness, and hot flashes.
Yes. All 503B compounding pharmacies (including ours) follow rigorous third-party testing and are regulated by the FDA, DEA, and state boards. Medications undergo potency, sterility, and quality checks before shipment.
Yes. Oestra® is compounded in a 503B FDA-regulated pharmacy that is also DEA-inspected and LegitScript certified. Each batch is tested for potency, purity, sterility, and consistency before shipping.
Disclaimer: Oestra® is a compounded prescription medication prepared by a licensed U.S. pharmacy.
Compounded medications are not evaluated or approved by the FDA but are regulated under federal and state pharmacy laws and prescribed on an individual basis.

One physician-formulated cream.
Two bioidentical hormones.
A steady daily routine designed to
support your body long-term
Start your treatment plan
No insurance needed. Cancel anytime.